Abstract

The effects of sublingual were assessed in 20 patients with severe hyperten - sion in emergency room setting. Sublingual nifedipine 10mg signi6ficandy reduced the systolic and diastolic blood pressures from 15 minutes after administration in all patients. The maximal lowering effects were seen at 1 and halfhour after administration (45.3/34.4mmHg, 22% / 27%). Heart rate did not change significantly except mild in crease in 45 and 60 minutes after administration No serious unwanted effects were observed Nifedipi- ne is a simple, effective and safe alternative drug for managing hypertensive emergencies especially in general practice or amall sized emergency rooms.