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The Asenze Cohort Study in KwaZulu-Natal, South Africa: protocol and cohort profile
Chris Desmond, Gabriella A. Norwitz, Jane D. Kvalsvig, Rachel S. Gruver, Shuaib Kauchali, Kathryn G. Watt, Nonhlanhla P. Myeza, Adele Munsami, Leslie L. Davidson
Epidemiol Health. 2022;44:e2022037.   Published online April 5, 2022
DOI: https://doi.org/10.4178/epih.e2022037
  • 3,628 View
  • 216 Download
AbstractAbstract PDF
Abstract
The Asenze cohort is set in South Africa, a middle-income country impacted by one of the highest global rates of people living with HIV/AIDS and high levels of socioeconomic inequality. This longitudinal population-based cohort of children and their primary caregivers assesses household and caregiver functioning, child health, social well-being, and neuro-development from childhood through adolescence. Almost 1,600 children born at the peak of the human immunodeficiency virus epidemic (2003-2005) were followed (with their primary caregivers) in 3 waves, between 2008 and 2021, at average ages of 5, 7, and 16. Wave 3 is currently underway, having assessed over 1,100 of the original wave 1 children. Wave 4 begins in 2022. The study, with a dyadic structure, uses a broad range of measures, validated in South Africa or recommended for global use, that address physical, social and neuro-development in childhood and adolescence, and the social, health, and psychological status of children’s primary caregivers. The Asenze study deepens our understanding of childhood physical, cognitive, and social abilities and/or disabilities, including risk-taking behaviors, and biological, environmental, and social determinants of health. We anticipate the findings will contribute to the development of community-informed interventions to promote well-being in this South African population and elsewhere.
Summary
Korean summary
Key Message
The Asenze Cohort Study, one of a limited number of population-based studies set in low- and middle-income countries, with a high level of retention, provides an understanding of neuro-developmental, psychosocial, home environmental and economic exposures and outcomes of over 1100 adolescents and their primary caregivers in KwaZulu-Natal, South Africa.
Cohort profile: Singapore’s nationally representative Retirement and Health Study with 5 waves over 10 years
Reuben Ng, Yi Wen Tan, Kelvin Bryan Tan
Epidemiol Health. 2022;44:e2022030.   Published online February 21, 2022
DOI: https://doi.org/10.4178/epih.e2022030
  • 2,930 View
  • 218 Download
  • 4 Citations
AbstractAbstract PDF
Abstract
The Retirement and Health Study (RHS) is Singapore’s largest nationally representative cohort with over 15,000 participants (aged 45-85 years) followed across five timepoints in 10 years (2014-2024). Accounting for sample weights, the sample represents 1.2 million Singaporeans and permanent residents of a total population of 5.5 million. The RHS sought consent to link survey responses to relevant administrative data, enabling the cross-validation of self-reports with national databases. There are 10 sections in the RHS with over 400 questions, 50% of which are on respondents’ physical and mental health, healthcare utilization and insurance; the remaining 50% are about employment history, retirement adequacy, wealth, and household expenditure. The RHS was set up to provide microdata to compliment administrative data for whole-of-government policy making given that Singapore will reach super-aged status by 2026. Sample findings include a need for older adults to balance between immediate financial needs and investments regarding their pension funds. Also, 86% of older adults preferred to transit into partial retirement by reducing workloads. On the health front, existing studies utilising the RHS have revealed latent classes of disabilities, and that intentions to seek employment can mitigate disability developments. Another study reported that physical disability and social isolation was projected to increase, with ethnic disparities in social functioning. Overall, the RHS will be used for evidenced-informed policy agenda setting and evaluation across domains of health, finance, retirement adequacy, social and family development.
Summary
Korean summary
Key Message
The Retirement and Health Study (RHS) is Singapore’s largest nationally representative cohort with over 15,000 participants (aged 45-85 years) followed across five timepoints in 10 years (2014-2024). Sample findings include a need for older adults to balance between immediate financial needs and investments regarding their pension funds. Overall, the RHS will be used for evidenced-informed policy agenda setting and evaluation across domains of health, finance, retirement adequacy, social and family development.

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  • Not Too Old for TikTok: How Older Adults Are Reframing Aging
    Reuben Ng, Nicole Indran, Barbara J Bowers
    The Gerontologist.2022; 62(8): 1207.     CrossRef
  • A playbook for effective age advocacy on Twitter
    Reuben Ng, Nicole Indran, Luyao Liu
    Journal of the American Geriatrics Society.2022; 70(8): 2363.     CrossRef
  • Ageism on Twitter during the COVID‐19 pandemic
    Reuben Ng, Nicole Indran, Luyao Liu
    Journal of Social Issues.2022; 78(4): 842.     CrossRef
  • Media attention toward COVID-19 across 18 countries: The influence of cultural values and pandemic severity
    Reuben Ng, Yi Wen Tan, Miguel A. Andrade-Navarro
    PLOS ONE.2022; 17(12): e0271961.     CrossRef
The Dehgolan Prospective Cohort Study (DehPCS) on non-communicable diseases in a Kurdish community in the west of Iran
Farhad Moradpour, Ebrahim Ghaderi, Ghobad Moradi, Mojdeh Zarei, Amjad Mohamadi Bolbanabad, Bakhtiar Piroozi, Azad Shokri
Epidemiol Health. 2021;43:e2021075.   Published online October 1, 2021
DOI: https://doi.org/10.4178/epih.e2021075
  • 5,364 View
  • 88 Download
  • 3 Citations
AbstractAbstract PDF
Abstract
The Dehgolan Prospective Cohort Study (DehPCS) was conducted to examine and identify risk factors for the most prevalent non-communicable diseases (NCDs). In addition, in order to examine participants’ health status, socioeconomic status, behavioral factors, nutritional status, and environmental exposures, the DehPCS collected, analyzed, and stored blood, urine, nail, and hair samples to conduct genetic studies and identify biomarkers and other biological determinants of NCDs. In total, 3,996 adults aged 35 to 70 from the general population participated in the study from February 2018 to March 2019. Of them, 43.7% were women. The first follow-up wave was conducted with 3,995 participants. Information on a wide range of variables was collected, including on socioeconomic status, lifestyle, nutritional status, habits, physical examination findings, medication use, and medical history. Proxy variables such as body mass index, metabolic equivalent task score, wealth index, and macronutrients and micronutrients were calculated. The most common self-reported diseases in descending order were kidney stones, hypertension, and fatty liver. The prevalence of diabetes and hypertension was 9.3% and 33.4%, respectively. All data, samples, and measurements will be collected again at 5-year intervals. Thus, it will be possible to examine time-dependent changes in the risk factors of NCDs. The DehPCS can be used to study the relationships among genetics, lifestyle, socioeconomic status, and environmental risk factors and the most prevalent NCDs in case-cohort studies using a nested case-control design that will be applied to the cohort infrastructure. Researchers can also submit pre-proposals via the following web address: http://c.ddrc.ac.ir/persianaccess/Account/Login.
Summary
Korean summary
Key Message
• The DehPCS was designed to examine NCDs among the Kurdish population, who are located in a wide area between the northwest of the Zagros Mountains and the eastern Taurus Mountains covering Turkey, Iraq, Iran, and Syria. • In total, 3,996 adults aged 35 to 70 from the general population participated in the study. • All data, samples, and measurements from the registration phase will be collected again at 5-, 10-, and 15-year intervals. • After labeling, aliquots were placed in a freezer at -70°C to enable ongoing studies of the samples in the future.

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  • Validity of self‐reported hypertension and related factors in the adult population: Preliminary results from the cohort in the west of Iran
    Negar Piri, Yousef Moradi, Reza Ghanei Gheshlagh, Mahsa Abdullahi, Eghbal Fattahi, Farhad Moradpour
    The Journal of Clinical Hypertension.2023; 25(2): 146.     CrossRef
  • Socio-demographic correlates of diabetes self-reporting validity: a study on the adult Kurdish population
    Farhad Moradpour, Negar Piri, Hojat Dehghanbanadaki, Ghobad Moradi, Mahdiyeh Fotouk-Kiai, Yousef Moradi
    BMC Endocrine Disorders.2022;[Epub]     CrossRef
  • Prevalence of prediabetes, diabetes, diabetes awareness, treatment, and its socioeconomic inequality in west of Iran
    Farhad Moradpour, Satar Rezaei, Bakhtiar Piroozi, Ghobad Moradi, Yousef Moradi, Negar Piri, Azad Shokri
    Scientific Reports.2022;[Epub]     CrossRef
Cohort profile: the Environmental-Pollution-Induced Neurological EFfects (EPINEF) study: a multicenter cohort study of Korean adults
Heeseon Jang, Woojin Kim, Jaelim Cho, Jungwoo Sohn, Juhwan Noh, Gayoung Seo, Seung-Koo Lee, Young Noh, Sung Soo Oh, Sang-Baek Koh, Hee Jin Kim, Sang Won Seo, Ho Hyun Kim, Jung Il Lee, Sun-Young Kim, Changsoo Kim
Epidemiol Health. 2021;43:e2021067.   Published online September 16, 2021
DOI: https://doi.org/10.4178/epih.e2021067
  • 5,991 View
  • 204 Download
  • 2 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The general population is exposed to numerous environmental pollutants, and it remains unclear which pollutants affect the brain, accelerating brain aging and increasing the risk of dementia. The Environmental-Pollution-Induced Neurological Effects study is a multi-city prospective cohort study aiming to comprehensively investigate the effect of different environmental pollutants on brain structures, neuropsychological function, and the development of dementia in adults. The baseline data of 3,775 healthy elderly people were collected from August 2014 to March 2018. The eligibility criteria were age ≥50 years and no self-reported history of dementia, movement disorders, or stroke. The assessment included demographics and anthropometrics, laboratory test results, and individual levels of exposure to air pollution. A neuroimaging sub-cohort was also recruited with 1,022 participants during the same period, and brain magnetic resonance imaging and neuropsychological tests were conducted. The first follow-up environmental pollutant measurements will start in 2022 and the follow-up for the sub-cohort will be conducted every 3-4 years. We have found that subtle structural changes in the brain may be induced by exposure to airborne pollutants such as particulate matter 10 μm or less in diameter (PM10), particulate matter 2.5 μm or less in diameter (PM2.5) and Mn10, manganese in PM10; Mn2.5, manganese in PM2.5. PM10, PM2.5, and nitrogen dioxide in healthy adults. This study provides a basis for research involving large-scale, long-term neuroimaging assessments in community-based populations.
Summary
Korean summary
EPINEF 코호트는 환경유해인자에 의한 신경계 질환의 위해성을 평가하고, 환경유해인자로 유발되는 신경심리학적 기능 저하 또는 뇌 노화에 대한 근거를 제공하기 위해 2014년부터 50세 이상의 건강한 성인을 대상으로 시작되었습니다. 본 코호트는 뇌 영상학적 표지자와 인지 기능과 관련된 환경유해인자를 광범위하게 조사한 한국 최초의 장기 추적관찰 연구로, 대기 오염 물질 또는 다환방향족탄화수소 노출이 대뇌 영상표지자 및 신경심리학적 기능, 노인의 우울 증상에 대한 악화 요인으로서의 대기오염물질 노출과 결혼 상태의 교호작용 등의 연구결과들을 발표하였습니다. 또한, 추후에도 코호트의 지속적인 추적을 통해 환경유해인자 노출에 따른 신경학적 건강영향을 연구하여, 신경계 질환 관리를 위한 보건 정책 개선에 기여할 수 있을 것으로 기대됩니다.
Key Message
The EPINEF cohort was started in 2014 to assess the risk of neurological diseases caused by environmental harmful factors and to provide evidence for neuropsychological dysfunction or brain aging induced by these factors. This cohort is the first long-term follow-up study in Korea to extensively investigate brain imaging markers and environmental harmful factors related to cognitive function, and several related research results have been published. In addition, the follow-up survey will be continued in the future, and we expect that the results of the study will contribute to improving health policies for the management of neurological diseases.

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  • Surveillance of long-term environmental elements and PM2.5 health risk assessment in Yangtze River Delta, China, from 2016 to 2020
    Keqin Wu, Yuanhua Meng, Yan Gong, Xuhui Zhang, Linlin Wu, Xinliang Ding, Xiaofeng Chen
    Environmental Science and Pollution Research.2022; 29(54): 81993.     CrossRef
  • Reduced brain subcortical volumes in patients with glaucoma: a pilot neuroimaging study using the region-of-interest-based approach
    Yae Won Ha, Heeseon Jang, Sang-Baek Koh, Young Noh, Seung-Koo Lee, Sang Won Seo, Jaelim Cho, Changsoo Kim
    BMC Neurology.2022;[Epub]     CrossRef
Cohort profile: the Ewha Birth and Growth Study
Hye Ah Lee, Bohyun Park, Jungwon Min, Eun Jeong Choi, Ui Jeong Kim, Hyun Jin Park, Eun Ae Park, Su Jin Cho, Hae Soon Kim, Hwayoung Lee, Young Ju Kim, Young Sun Hong, Eui-Jung Kim, Eun Hee Ha, Hyesook Park
Epidemiol Health. 2021;43:e2021016.   Published online February 22, 2021
DOI: https://doi.org/10.4178/epih.e2021016
  • 8,414 View
  • 350 Download
  • 7 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
With the introduction of life-course epidemiology, researchers realized the importance of identifying risk factors in early life to prevent chronic diseases. This led to the establishment of the Ewha Birth and Growth Study in 2001; the study is a prospective birth cohort designed to provide evidence of early life risk factors for a child’s growth and health. Participants were recruited from those who visited Ewha Womans University Mokdong Hospital (a tertiary hospital in southwest Seoul, Korea) for prenatal care at 24-28 weeks of gestation. In total, 891 mothers enrolled in this study between 2001 and 2006 and their offspring (n=940) were followed-up. Regular check-up examinations of offspring were conducted at 3 years, 5 years, and 7 years of age and every year thereafter. To consider age-related health issues, extensive data were collected using questionnaires and measurements. In 2021, the study subjects will reach 19 years of age, and we are planning a check-up examination for early adulthood. About 20 years have passed since the cohort data were collected, and we have published results on childhood health outcomes associated with prenatal and birth characteristics, genetic and epigenetic characteristics related to childhood metabolism, the effects of exposure to endocrine disruptors, and dietary patterns in childhood. Recently, we started reporting on topics related to adolescent health. The findings will facilitate identification of early life risk factors for chronic diseases and the development of interventions for diseases later in life.
Summary
Korean summary
이화영아성장코호트는 만성질환 예방을 위한 생애초기 위험인자에 대한 근거를 제공하기 위해 2001년에 시작되었습니다. 이화영아성장코호트는 국내에서 선도적인 장기 추적관찰 연구로, 소아기 건강과 관련된 산전 및 출생 시 특징, 소아기 대사와 관련된 유전적 혹은 후성학적 특성, 내분비 장애물질 노출에 따른 영향, 소아기의 식이패턴과 같은 다양한 연구결과들을 발표하였습니다. 추후 청년기의 자료 수집을 계획하고 있으며, 우리의 연구결과는 만성질환 예방을 위한 중재 개발에 기여할 것으로 기대됩니다.
Key Message
To provide evidence of early life risk factors for the prevention of chronic diseases, the Ewha Birth and Growth Study was started in 2001. The Ewha Birth and Growth cohort is a leading long-term follow-up study in Korea, and we have published results on childhood health outcomes associated with prenatal and birth characteristics, genetic and epigenetic characteristics related to childhood metabolism, the effects of exposure to endocrine disruptors, and dietary patterns in childhood. We are planning to collect data for early adulthood, and our findings will contribute to the development of interventions to prevent chronic diseases.

Citations

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  • Prospective association between phthalate exposure in childhood and liver function in adolescence: the Ewha Birth and Growth Cohort Study
    Seonhwa Lee, Hye Ah Lee, Bohyun Park, Hyejin Han, Young Sun Hong, Eun Hee Ha, Hyesook Park
    Environmental Health.2023;[Epub]     CrossRef
  • BMI trajectory and inflammatory effects on metabolic syndrome in adolescents
    Ui-Jeong Kim, Eun Jeong Choi, Hyunjin Park, Hye Ah Lee, Bohyun Park, Jungwon Min, Eun Ae Park, Su Jin Cho, Hae Soon Kim, Hwayoung Lee, Young Ju Kim, Young Sun Hong, Eun Hee Ha, Seungyoun Jung, Hyesook Park
    Pediatric Research.2023;[Epub]     CrossRef
  • The Effect of Childhood Obesity or Sarcopenic Obesity on Metabolic Syndrome Risk in Adolescence: The Ewha Birth and Growth Study
    Hyunjin Park, Seunghee Jun, Hye-Ah Lee, Hae Soon Kim, Young Sun Hong, Hyesook Park
    Metabolites.2023; 13(1): 133.     CrossRef
  • The Mediating Effect of Inflammation between the Dietary and Health-Related Behaviors and Metabolic Syndrome in Adolescence
    Ui-Jeong Kim, Eun-Jeong Choi, Hyunjin Park, Hye-Ah Lee, Bomi Park, Haesoon Kim, Youngsun Hong, Seungyoun Jung, Hyesook Park
    Nutrients.2022; 14(11): 2339.     CrossRef
  • Precision medicine via the integration of phenotype-genotype information in neonatal genome project
    Xinran Dong, Tiantian Xiao, Bin Chen, Yulan Lu, Wenhao Zhou
    Fundamental Research.2022; 2(6): 873.     CrossRef
  • Association of participation in the Northern Finland Birth Cohort 1986 with mental disorders and suicidal behaviour
    Martta Kerkelä, Mika Gissler, Juha Veijola
    Epidemiology and Health.2022; 44: e2022005.     CrossRef
  • Trajectory patterns for continuous metabolic syndrome score in childhood and the cardiovascular risk in adolescence
    Eun Jeong Choi, Hye Ah Lee, Bomi Park, Bohyun Park, Hae Soon Kim, Young Sun Hong, Hyesook Park
    Scientific Reports.2021;[Epub]     CrossRef
Cohort profile: congenital Zika virus infection and child neurodevelopmental outcomes in the ZEN cohort study in Colombia
Maritza Gonzalez, Van T. Tong, Helena Rodriguez, Diana Valencia, Jacqueline Acosta, Margaret A. Honein, Martha L. Ospina
Epidemiol Health. 2020;42:e2020060.   Published online August 31, 2020
DOI: https://doi.org/10.4178/epih.e2020060
  • 8,070 View
  • 198 Download
  • 2 Citations
AbstractAbstract PDF
Abstract
Zika en Embarazadas y Niños (ZEN) is a prospective cohort study designed to identify risk factors and modifiers for Zika virus (ZIKV) infection in pregnant women, partners, and infants, as well as to assess the risk for adverse maternal, fetal, infant, and childhood outcomes of ZIKV and other congenital infections. ZIKV infection during pregnancy may be associated with longterm sequelae. In the ZEN cohort, 1,519 pregnant women and 287 partners were enrolled from 3 departments within Colombia between February 2017 and January 2018, as well as 1,108 infants born to the pregnant women who were followed to 6 months. The data include baseline questionnaires at enrollment; repeated symptoms and study follow-up questionnaires; the results of lab tests to detect ZIKV and other congenital infections; medical record abstractions; infant physical, eye, and hearing exams; and developmental screening tests. Follow-up of 850 mother-child dyads occurred at 9 months, 12 months, and 18 months with developmental screenings, physical exams, and parent questionnaires. The data will be pooled with those from other prospective cohort studies for an individual participant data meta-analysis of ZIKV infection during pregnancy to characterize pregnancy outcomes and sequelae in children.
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  • Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia
    Angelica Rico, Sheila C. Dollard, Diana Valencia, Sheryll Corchuelo, Van T. Tong, Katherine Laiton‐Donato, Minal M. Amin, Monica Benavides, Phili Wong, Suzanne Newton, Marcela Daza, Jordan Cates, Maritza Gonzalez, Laura D. Zambrano, Marcela M. Mercado, El
    Journal of Medical Virology.2021; 93(11): 6393.     CrossRef
  • Causes of Phenotypic Variability and Disabilities after Prenatal Viral Infections
    Youssef A. Kousa, Reafa A. Hossain
    Tropical Medicine and Infectious Disease.2021; 6(2): 95.     CrossRef
Cohort profile: the Kisalaya cohort of mother-infant dyads in rural south India (2008-2012)
Smitha Chandrashekarappa, Krupa Modi, Karl Krupp, Kavitha Ravi, Anisa Khan, Vijaya Srinivas, Poornima Jaykrishna, Anjali Arun, Murali Krishna, Purnima Madhivanan
Epidemiol Health. 2020;42:e2020010.   Published online March 11, 2020
DOI: https://doi.org/10.4178/epih.e2020010
  • 8,488 View
  • 153 Download
AbstractAbstract PDF
Abstract
The Kisalaya cohort was established in 2008, providing integrated antenatal care (ANC) and human immunodeficiency virus (HIV) testing in order to reduce adverse birth outcomes and pediatric HIV infections. The program used a mobile clinic model to deliver health education, ANC, and HIV/sexually transmitted infection testing and management to pregnant women in rural communities in southern India. This cohort includes pregnant women residing in 144 villages of the Mysuru taluk (a rural region) who received ANC through the mobile clinic and delivered their infants between 2008 and 2011. Of the 1,940 women registered for ANC at primary healthcare centers during this time period, 1,675 (75.6%) were enrolled in the Kisalaya cohort. Once women enrolled in the Kisalaya cohort gave birth, the cohort expanded to include the mother-infant dyads with a retention rate of 100% at follow-up visits at 15 days and at 6 months post-delivery. The baseline data collected during the Kisalaya study included both questionnaire-based data and laboratory-based investigations. Presently, a study entitled “Early life influences on adolescent mental health: a life course study of the Kisalaya birth cohort in south India” is in the process of data collection (2019-2020).
Summary
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Key Message
Health Effects of Underground Workspaces cohort: study design and baseline characteristics
Gerard Dunleavy, Thirunavukkarasu Sathish, Nuraini Nazeha, Michael Soljak, Nanthini Visvalingam, Ram Bajpai, Hui Shan Yap, Adam C. Roberts, Thuan Quoc Thach, André Comiran Tonon, Chee Kiong Soh, Georgios Christopoulos, Kei Long Cheung, Hein de Vries, Josip Car
Epidemiol Health. 2019;41:e2019025.   Published online August 16, 2019
DOI: https://doi.org/10.4178/epih.e2019025
  • 11,945 View
  • 178 Download
  • 13 Citations
AbstractAbstract PDFSupplementary Material
Abstract
The development of underground workspaces is a strategic effort towards healthy urban growth in cities with ever-increasing land scarcity. Despite the growth in underground workspaces, there is limited information regarding the impact of this environment on workers’ health. The Health Effects of Underground Workspaces (HEUW) study is a cohort study that was set up to examine the health effects of working in underground workspaces. In this paper, we describe the rationale for the study, study design, data collection, and baseline characteristics of participants. The HEUW study recruited 464 participants at baseline, of whom 424 (91.4%) were followed-up at 3 months and 334 (72.0%) at 12 months from baseline. We used standardized and validated questionnaires to collect information on socio-demographic and lifestyle characteristics, medical history, family history of chronic diseases, sleep quality, health-related quality of life, chronotype, psychological distress, occupational factors, and comfort levels with indoor environmental quality parameters. Clinical and anthropometric parameters including blood pressure, spirometry, height, weight, and waist and hip circumference were also measured. Biochemical tests of participants’ blood and urine samples were conducted to measure levels of glucose, lipids, and melatonin. We also conducted objective measurements of individuals’ workplace environment, assessing air quality, light intensity, temperature, thermal comfort, and bacterial and fungal counts. The findings this study will help to identify modifiable lifestyle and environmental parameters that are negatively affecting workers’ health. The findings may be used to guide the development of more health-promoting workspaces that attempt to negate any potential deleterious health effects from working in underground workspaces.
Summary
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  • Effects of fun-seeking and external locus of control on smoking behaviour: a cross-sectional analysis on a cohort of working men in Singapore
    Kar Fye Alvin Lee, Eun Hee Lee, Adam Charles Roberts, Josip Car, Chee Kiong Soh, Georgios Christopoulos
    BMJ Open.2022; 12(10): e061318.     CrossRef
  • A Comparative Study of International and Asian Criteria for Overweight or Obesity at Workplaces in Singapore
    Nuraini Nazeha, Thirunavukkarasu Sathish, Michael Soljak, Gerard Dunleavy, Nanthini Visvalingam, Ushashree Divakar, Ram Chandra Bajpai, Chee Kiong Soh, George Christopoulos, Josip Car
    Asia Pacific Journal of Public Health.2021; 33(4): 404.     CrossRef
  • Prevalence of and factors associated with poor sleep quality and short sleep in a working population in Singapore
    Nanthini Visvalingam, Thirunavukkarasu Sathish, Michael Soljak, Ai-Ping Chua, Gerard Dunleavy, Ushashree Divakar, Nuraini Nazeha, Ram Bajpai, Chee Kiong Soh, Kwok Kian Woon, Georgios Christopoulos, Josip Car
    Sleep Health.2020; 6(3): 277.     CrossRef
  • Activity Tracker–Based Metrics as Digital Markers of Cardiometabolic Health: Cross-Sectional Study
    Yuri Rykov, Thuan-Quoc Thach, Gerard Dunleavy, Adam Charles Roberts, George Christopoulos, Chee Kiong Soh, Josip Car
    JMIR mHealth and uHealth.2020; 8(1): e16409.     CrossRef
  • Prevalence of psychological distress and its association with perceived indoor environmental quality and workplace factors in under and aboveground workplaces
    Gerard Dunleavy, Ram Bajpai, André Comiran Tonon, Kei Long Cheung, Thuan-Quoc Thach, Yuri Rykov, Chee-Kiong Soh, Hein de Vries, Josip Car, Georgios Christopoulos
    Building and Environment.2020; 175: 106799.     CrossRef
  • Employee experiences in underground workplaces: a qualitative investigation
    Vinita Venugopal, Adam Charles Roberts, Kian-Woon Kwok, George I. Christopoulos, Chee-Kiong Soh
    Ergonomics.2020; 63(11): 1337.     CrossRef
  • Associations of perceived indoor environmental quality with stress in the workplace
    Thuan‐Quoc Thach, Dhiya Mahirah, Charlotte Sauter, Adam Charles Roberts, Gerard Dunleavy, Nuraini Nazeha, Yuri Rykov, Yichi Zhang, George I. Christopoulos, Chee‐Kiong Soh, Josip Car
    Indoor Air.2020; 30(6): 1166.     CrossRef
  • White- and Blue- collar workers responses’ towards underground workspaces
    Ying Su, Adam C. Roberts, Hui Shan Yap, Josip Car, Kian Woon Kwok, Chee-Kiong Soh, George I. Christopoulos
    Tunnelling and Underground Space Technology.2020; 105: 103526.     CrossRef
  • Prevalence of sick building syndrome and its association with perceived indoor environmental quality in an Asian multi-ethnic working population
    Thuan-Quoc Thach, Dhiya Mahirah, Gerard Dunleavy, Nuraini Nazeha, Yichi Zhang, Christina En Hui Tan, Adam Charles Roberts, George Christopoulos, Chee Kiong Soh, Josip Car
    Building and Environment.2019; 166: 106420.     CrossRef
  • A Multifactorial Approach to Sleep and Its Association with Health-Related Quality of Life in a Multiethnic Asian Working Population: A Cross-Sectional Analysis
    Gerard Dunleavy, André Comiran Tonon, Ai Ping Chua, Yichi Zhang, Kei Long Cheung, Thuan-Quoc Thach, Yuri Rykov, Chee-Kiong Soh, Georgios Christopoulos, Hein de Vries, Josip Car
    International Journal of Environmental Research and Public Health.2019; 16(21): 4147.     CrossRef
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    Thirunavukkarasu Sathish, Gerard Dunleavy, Michael Soljak, Nanthini Visvalingam, Nuraini Nazeha, Ushashree Divakar, Ram Bajpai, Thuan-Quoc Thach, Kei Cheung, Hein Vries, Chee-Kiong Soh, Georgios Christopoulos, Josip Car
    International Journal of Environmental Research and Public Health.2019; 16(22): 4551.     CrossRef
  • Examining the Factor Structure of the Pittsburgh Sleep Quality Index in a Multi-Ethnic Working Population in Singapore
    Dunleavy, Bajpai, Tonon, Chua, Cheung, Soh, Christopoulos, Vries, Car
    International Journal of Environmental Research and Public Health.2019; 16(23): 4590.     CrossRef
  • Prevalence of Vitamin D Deficiency and Its Associated Work-Related Factors among Indoor Workers in a Multi-Ethnic Southeast Asian Country
    Ushashree Divakar, Thirunavukkarasu Sathish, Michael Soljak, Ram Bajpai, Gerard Dunleavy, Nanthini Visvalingam, Nuraini Nazeha, Chee Kiong Soh, Georgios Christopoulos, Josip Car
    International Journal of Environmental Research and Public Health.2019; 17(1): 164.     CrossRef
The Mysuru stUdies of Determinants of Health in Rural Adults (MUDHRA), India
Padukudru Anand Mahesh, Komarla Sundararaja Lokesh, Purnima Madhivanan, Sindaghatta Krishnarao Chaya, Biligere Siddaiah Jayaraj, Koustav Ganguly, Murali Krishna
Epidemiol Health. 2018;40:e2018027.   Published online June 23, 2018
DOI: https://doi.org/10.4178/epih.e2018027
  • 10,035 View
  • 192 Download
  • 12 Citations
AbstractAbstract PDF
Abstract
Between 2006 and 2010, in 16 randomly selected villages in rural areas of Mysore district, in south India, 8,457 subjects aged 30 and above were screened for symptoms of chronic respiratory disease. Of the 8,457 subjects, 1,692 were randomly invited for further evaluation of lung function and chronic obstructive pulmonary disease (COPD) by spirometry, and 1,085 of these subjects underwent lung function assessments for prevalent COPD and its risk factors. These 1,085 subjects, who were then aged between 35 and 80 years, constituted the Mysuru stUdies of Determinants of Health in Rural Adults (MUDHRA) cohort. Among other findings, threshold of biomass fuel smoke exposure suitable for use as a dichotomous risk factor for the diagnosis of chronic bronchitis was established, with a minimum biomass smoke exposure index of 60 found to be significantly associated with an elevated risk of developing chronic bronchitis. Five years later (between 2014 and 2016), 869 of the 1,085 participants were followed up with repeat lung function assessments for incident COPD and all-cause mortality. A subset of these participants (n=200) underwent blood tests for vitamin D levels, antioxidant activity, an assessment for anxiety and depression, and another subset (n=98) underwent a bioplex assay for 40 serum cytokines.
Summary
Korean summary
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    Komarla Sundararaja Lokesh, Ananya Ananth Rao, Sindaghatta Krishnarao Chaya, Biligere Siddaiah Jayaraj, Attahalli Shivanarayanprasad Praveena, Murali Krishna, Purnima Madhivanan, Mahesh Padukudru Anand
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    Marta Entrenas-Castillo, Lourdes Salinero-González, Luis M. Entrenas-Costa, Rubén Andújar-Espinosa
    Nutrients.2022; 14(12): 2447.     CrossRef
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    Arshad Sattar Lakho , Akbar Gohar Abro , Abdul Hafeez Thebo, Khalil Kazi , Saba Bashir, Ghulam Shahar Bano
    Pakistan BioMedical Journal.2022; : 107.     CrossRef
  • Exploring the links between indoor air pollutants and health outcomes in South Asian countries: a systematic review
    Laiba Rafiq, Syeda Hamayal Zahra Naqvi, Laila Shahzad, Syed Mustafa Ali
    Reviews on Environmental Health.2022;[Epub]     CrossRef
  • Vitamin D deficiency is associated with chronic obstructive pulmonary disease and exacerbation of COPD
    Komarla Sundararaja Lokesh, Sindaghatta Krishnarao Chaya, Biligere Siddaiah Jayaraj, Attahalli Shivanarayanprasad Praveena, Murali Krishna, Purnima Madhivanan, Padukudru Anand Mahesh
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    Brett T. Doherty, Jeremy P. Koelmel, Elizabeth Z. Lin, Megan E. Romano, Krystal J. Godri Pollitt
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  • Inflammatory Biomarkers Interleukin 1 Beta (IL-1β) and Tumour Necrosis Factor Alpha (TNF-α) Are Differentially Elevated in Tobacco Smoke Associated COPD and Biomass Smoke Associated COPD
    Bellipady Shyam Prasad Shetty, Sindaghatta Krishnarao Chaya, Sravan Kumar V, Maheswarappa Mahendra, Biligere Siddaiah Jayaraj, Komarla Sundararaja Lokesh, Koustav Ganguly, Padukudru Anand Mahesh
    Toxics.2021; 9(4): 72.     CrossRef
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    Ashwani Verma, Nachiket Gudi, Uday N Yadav, Manas Pratim Roy, Amreen Mahmood, Ravishankar Nagaraja, Pradeepa Nayak
    Journal of Global Health.2021;[Epub]     CrossRef
  • Household air pollution in India and respiratory diseases
    Surinder K. Jindal, Ashutosh N. Aggarwal, Aditya Jindal
    Current Opinion in Pulmonary Medicine.2020; 26(2): 128.     CrossRef
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    BharatBhushan Sharma, Sheetu Singh, KrishnaKumar Sharma, KP Suraj, Tariq Mahmood, KumarUtsav Samaria, Surya Kant, Nishtha Singh, Tejraj Singh, Aradhna Singh, Rajeev Gupta, ParvaizA Koul, Sundeep Salvi, Virendra Singh, SWORD Study Group
    Lung India.2020; 37(2): 100.     CrossRef
  • Clinical, Epidemiological and Experimental Approaches to Assess Adverse Health Outcomes of Indoor Biomass Smoke Exposure: Conclusions from An Indo-Swedish Workshop in Mysuru, January 2020
    Mahesh Padukudru Anand, Kjell Larsson, Gunnar Johanson, Harish C. Phuleria, P. Veeranna Ravindra, Lena Ernstgård, Ulaganathan Mabalirajan, Murali Krishna, Lena Palmberg, Krystal J. Godri Pollitt, Swapna Upadhyay, Koustav Ganguly
    Toxics.2020; 8(3): 68.     CrossRef
  • Putative Systemic Biomarkers of Biomass Smoke-Induced Chronic Obstructive Pulmonary Disease among Women in a Rural South Indian Population
    Sangeetha Vishweswaraiah, Tania Ahalya Thimraj, Leema George, Chaya Sindaghatta Krishnarao, Komarla Sundararaja Lokesh, Jayaraj Biligere Siddaiah, Kjell Larsson, Swapna Upadhyay, Lena Palmberg, Mahesh Padukudru Anand, Koustav Ganguly
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Korea HIV/AIDS Cohort Study: study design and baseline characteristics
Bo Youl Choi, Jun Yong Choi, Sang Hoon Han, Sang Il Kim, Mee-Kyung Kee, Min Ja Kim, Shin-Woo Kim, Sung Soon Kim, Yu-Mi Kim, Nam Su Ku, Jin-Soo Lee, Joo-Shil Lee, Yunsu Choi, Kyong Sil Park, Joon Young Song, Jun Hee Woo, Moon Won Kang, June Kim
Epidemiol Health. 2018;40:e2018023.   Published online June 6, 2018
DOI: https://doi.org/10.4178/epih.e2018023
  • 12,385 View
  • 345 Download
  • 8 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The number of persons infected by HIV/AIDS has consistently increased in Korea since the first case of HIV/AIDS infection in 1985 and reached 15,208 by 2016. About 1,100 new patients with HIV/ AIDS infections have emerged every year since 2013. In Korea, the Korea HIV/AIDS Cohort Study was established for the evidenced-based prevention, treatment, and effective management of patients infected with human immunodeficiency virus (HIV) in December 2006. This study monitored 1,438 patients, who accounted for about 10% of all patients with HIV/AIDS in Korea, for 10 years with the following aims: (1) to develop an administrative system for the establishment of a HIV/AIDS cohort-based study; (2) to standardize methodologies and the case report forms; and (3) to standardize multi-cohort data and develop a data cleaning method. This study aims to monitor at least 1,000 patients (excluding those for whom investigation had been completed) per year (estimated number of patients who can be monitored by January 2018: 939). By December 2016, the sex distribution was 93.3% for men, and 6.7% for women (gender ratio, 13.9:1.0), and 98.9% of all participants were Korean. More than 50.0% of the participants were confirmed as HIV positive after 2006. This study reports competitive, long-term research that aimed to develop policies for the prevention of chronic infectious diseases for patients with HIV. The data collected over the last decade will be used to develop indices for HIV treatment and health promotion.
Summary
Korean summary
세계적으로 HIV 감염인은 감소하고 있으나, 한국의 HIV 감염은 증가하여 2013년 이후 매년 1,000명이 넘는 신규 감염인이 보고되고 있다. HIV/AIDS 코호트 연구진은 2006년부터 HIV 감염인과 AIDS 환자를 대상으로 6개월 간격의 반복 조사를 시행하여 역학과 임상 자료를 수집하여 데이터베이스를 구축하고, 생물검체를 채취하여 인체자원은행에 보관하여, HIV/AIDS의 발생 기전을 구명하고, 자연사를 파악하며, 예방과 진단, 치료, 관리 방법을 개발하기 위한 기초와 임상, 역학 연구에 활용하고 있다.
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  • Effect of single tablet regimen on prescription trends for treatment-naïve patients with HIV/AIDS in Korea
    Kyung Sun Oh, Gi Hyeon Seo, Hee Kyoung Choi, Euna Han
    Scientific Reports.2022;[Epub]     CrossRef
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    Kyungmin Kim, Jungmin Woo
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
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    Ji Yun Bae, Soo Min Kim, Yunsu Choi, Jun Yong Choi, Sang Il Kim, Shin-Woo Kim, Bo Young Park, Bo Youl Choi, Hee Jung Choi
    Infection & Chemotherapy.2022; 54(3): 409.     CrossRef
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    Jun Hyoung Kim, Heeseon Jang, Jung Ho Kim, Joon Young Song, Shin-Woo Kim, Sang Il Kim, Bo Youl Choi, Jun Yong Choi
    Infection & Chemotherapy.2022; 54(3): 534.     CrossRef
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    Eunyoung Lee, Jungmee Kim, Jin Yong Lee, Ji Hwan Bang
    Journal of Korean Medical Science.2020;[Epub]     CrossRef
  • Human Immunodeficiency Virus-Associated Gastrointestinal Kaposi's Sarcoma: A Case Report
    Hee Joong Lim, So Hyun Park, Seung Joon Choi, Suyoung Park, Hee Young Lee, Jun Won Chung, Dong Hae Chung
    Journal of the Korean Society of Radiology.2020; 81(5): 1260.     CrossRef
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    Yunsu Choi, Bo Youl Choi, Soo Min Kim, Sang Il Kim, June Kim, Jun Young Choi, Shin-Woo Kim, Joon Young Song, Youn Jeong Kim, Dae Won Park, Hyo Youl Kim, Hee-Jung Choi, Mee-Kyung Kee, Young Hyun Shin, Myeongsu Yoo
    Epidemiology and Health.2019; 41: e2019037.     CrossRef
  • Comparison of Characteristics and Survival between Prospective and Retrospective Korea Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome Cohort Studies
    Jun Hyoung Kim, Yunsu Choi, Joon Young Song, Shin-Woo Kim, Sang Il Kim, Mee-Kyung Kee, Bo Youl Choi, Jun Yong Choi
    Infection & Chemotherapy.2019; 51(4): 393.     CrossRef
Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort: study protocol and results of the first 3 years of enrollment
Jee-Seon Shim, Bo Mi Song, Jung Hyun Lee, Seung Won Lee, Ji Hye Park, Dong Phil Choi, Myung Ha Lee, Kyoung Hwa Ha, Dae Jung Kim, Sungha Park, Won-Woo Lee, Hyeon Chang Kim
Epidemiol Health. 2017;39:e2017016.   Published online April 1, 2017
DOI: https://doi.org/10.4178/epih.e2017016
  • 14,230 View
  • 315 Download
  • 32 Citations
AbstractAbstract AbstractSummary PDF
Abstract
Although the etiologies of cardiovascular disease (CVD) are widely understood, the goal of finding a globally effective solution for preventing CVD is unrealistic. Therefore, we aimed to conduct a community-based prospective study on the prevention and management of CVD in Korean adults. This study was designed to recruit 8,000 healthy adults over the course of 5 years. The baseline assessment includes a wide range of established CVD risk factors, including demographic characteristics, medical history, health behaviors, psychological conditions, body size and composition, blood pressure, the augmentation index, carotid ultrasonography, an electrocardiogram, and biochemical indicators, as well as some novel factors, such as social network characteristics, exposure to environmental pollutants, inflammatory markers, hemostatic markers, and immunosenescence markers. Annual telephone interviews and follow-up health examinations at 5-year intervals after the baseline assessment are planned to collect information on changes in health status and its determinants. Additionally, indirect follow-up using secondary data sources will be conducted to obtain information on health services utilization and death. So far, more than 6,000 adults have been enrolled during the first three and a half years, and almost all participants have been tracked by annual telephone follow-up surveys. The data have been uploaded to iCReaT, the clinical research information management system of the Korea National Institute of Health.
Summary
Korean summary
심뇌혈관 및 대사질환 원인연구센터(Cardiovascular and Metabolic Diseases Etiology Research Center)에서는 심뇌혈관질환 및 대사질환의 새로운 발병 원인을 찾고 효율적인 예방 전략을 개발하고자 코호트(CMERC cohort와 CMERC-HI cohort)를 구축하였다. 지역사회에 거주하는 만 30-64세 건강한 성인을 대상으로 하는 CMERC cohort는 2013년부터 2018년 까지 총 5년 동안 8000명 등록을 목표로 기반조사를 진행 중이며(2016년 12월 현재 6000여명 등록), 이미 알려진 다양한 위험요인 이외에 사회연결망 정보와 면역노화 관련 바이오마커 등 새로운 위험 요인에 관한 광범위한 정보가 수집되고 있다. CMERC cohort는 심뇌혈관 및 대사질환 예방연구의 기초자료로 활용되어 과학적 데이터에 근거한 예방 전략 수립에 기여하게 될 것이다.
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Citations

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    Sun Young Shim, Sun Jae Jung, Seung Up Kim, Hyeon Chang Kim
    Clinical Hypertension.2023;[Epub]     CrossRef
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    Eunji Kim, Youngrong Lee, Hyeon Chang Kim
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  • Association between Metabolically Healthy Obesity and Subclinical Atherosclerosis in the Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) Cohort
    Da Hea Seo, Yongin Cho, Seongha Seo, Seong Hee Ahn, Seongbin Hong, Kyung Hwa Ha, Jee-Seon Shim, Hyeon Chang Kim, Dae Jung Kim, So Hun Kim
    Journal of Clinical Medicine.2022; 11(9): 2440.     CrossRef
  • Association Between Social Network and Cognitive Function: A Cross-Sectional Assessment From the Cardiovascular and Metabolic Diseases Etiology Research Center Cohort (2013–2018)
    Jimin Kim, Ji Su Yang, Yoosik Youm, Dae Jung Kim, Hyeon Chang Kim, Sun Jae Jung
    Frontiers in Psychiatry.2022;[Epub]     CrossRef
  • Short-term Blood Pressure Variability and Incident CKD in Patients With Hypertension: Findings From the Cardiovascular and Metabolic Disease Etiology Research Center–High Risk (CMERC-HI) Study
    Jong Hyun Jhee, Donghwan Oh, Jiwon Seo, Chan Joo Lee, Min-Yu Chung, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Sungha Park, Tae-Hyun Yoo
    American Journal of Kidney Diseases.2022;[Epub]     CrossRef
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    Ga Hye Lee, Jee Youn Lee, Jiyeon Jang, Yeon Jun Kang, Seung Ah Choi, Hyeon Chang Kim, Sungha Park, Myoung Soo Kim, Won‐Woo Lee
    Clinical & Translational Immunology.2022;[Epub]     CrossRef
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    Ye Jin Jeon, Youngrong Lee, Ji Su Yang, Young Su Park, Sun Jae Jung
    Epidemiology and Health.2022; : e2022064.     CrossRef
  • Does serum vitamin D level affect the association between cardiovascular health and cognition? Results of the Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) study
    Y. J. Jeon, S. J. Jung, H. C. Kim
    European Journal of Neurology.2021; 28(1): 48.     CrossRef
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    Jong Hyun Jhee, Bo Young Nam, Chan Joo Lee, Jung Tak Park, Seung Hyeok Han, Shin‐Wook Kang, Sungha Park, Tae‐Hyun Yoo
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    Sun Jae Jung, Ga Bin Lee, Kristen Nishimi, Lori Chibnik, Karestan C. Koenen, Hyeon Chang Kim
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    Sun Jae Jung, Ye Jin Jeon, Ji Su Yang, Minseo Park, Kwanghyun Kim, Lori B. Chibnik, Hyeon Chang Kim, Karestan C. Koenen
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  • Stressful life events and serum triglyceride levels: the Cardiovascular and Metabolic Diseases Etiology Research Center cohort in Korea
    Naharin Sultana Anni, Sun Jae Jung, Jee-Seon Shim, Yong Woo Jeon, Ga Bin Lee, Hyeon Chang Kim
    Epidemiology and Health.2021; 43: e2021042.     CrossRef
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    Sun Young Shim, Ga Bin Lee, Jee-Seon Shim, Sun Jae Jung, Hyeon Chang Kim
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  • Stressful life events and augmentation index: results from the Cardiovascular and Metabolic Diseases Etiology Research Center
    Sun Jae Jung, Yongwoo Jeon, Gabin Lee, Jee-Seon Shim, Hyeon Chang Kim
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    Hye Rin Choi, Jung Hyun Lee, Hyung Keun Lee, Jong Suk Song, Hyeon Chang Kim
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  • Dose-Response Association between Smoking Cessation and Arterial Stiffness: The Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) Cohort
    Ga Bin Lee, Jee Seon Shim, Hyeon Chang Kim
    Korean Circulation Journal.2020; 50(4): 361.     CrossRef
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    Soo Kyoung Kim, Hyeon Chang Kim, Jee-Seon Shim, Dae Jung Kim
    The Korean Journal of Internal Medicine.2020; 35(2): 369.     CrossRef
  • Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in Korea
    Eung Joo Park, Hokyou Lee, Hyeon Chang Kim, Seung Soo Sheen, Sang Baek Koh, Ki Soo Park, Nam Han Cho, Cheol-Min Lee, Dae Ryong Kang
    International Journal of Environmental Research and Public Health.2020; 17(8): 2946.     CrossRef
  • Association between the Thigh Muscle and Insulin Resistance According to Body Mass Index in Middle-Aged Korean Adults
    Ji Eun Heo, Jee-Seon Shim, Hokyou Lee, Hyeon Chang Kim
    Diabetes & Metabolism Journal.2020; 44(3): 446.     CrossRef
  • Depressive symptoms, its sub-factors, and augmentation index: the modifying effects according to inflammatory markers
    Ye Jin Jeon, So Mi Jemma Cho, Yu Jin Lee, Hyeon Chang Kim, Sun Jae Jung
    Journal of Affective Disorders.2020; 272: 380.     CrossRef
  • Ambulatory blood pressure variability and risk of cardiovascular events, all-cause mortality, and progression of kidney disease
    Jong Hyun Jhee, Jiwon Seo, Chan Joo Lee, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Sungha Park, Tae-Hyun Yoo
    Journal of Hypertension.2020; 38(9): 1712.     CrossRef
  • Comparison of Computed Tomography-based Abdominal Adiposity Indexes as Predictors of Non-alcoholic Fatty Liver Disease Among Middle-aged Korean Men and Women
    Jongmin Baek, Sun Jae Jung, Jee-Seon Shim, Yong Woo Jeon, Eunsun Seo, Hyeon Chang Kim
    Journal of Preventive Medicine and Public Health.2020; 53(4): 256.     CrossRef
  • Effect of Smartphone-Based Lifestyle Coaching App on Community-Dwelling Population With Moderate Metabolic Abnormalities: Randomized Controlled Trial
    So Mi Jemma Cho, Jung Hyun Lee, Jee-Seon Shim, Hyungseon Yeom, Su Jin Lee, Yong Woo Jeon, Hyeon Chang Kim
    Journal of Medical Internet Research.2020; 22(10): e17435.     CrossRef
  • The Association of Adiponectin and Visceral Fat with Insulin Resistance and β-Cell Dysfunction
    Hyun Uk Moon, Kyoung Hwa Ha, Seung Jin Han, Hae Jin Kim, Dae Jung Kim
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Presence of Metabolic Syndrome Components Is Associated with Tooth Loss in Middle-Aged Adults
    Min-Jeong Cho, Youn-Hee Choi, Hyeon Chang Kim, Jee-Seon Shim, Atsuo Amano, Ji-Young Kim, Keun-Bae Song
    Yonsei Medical Journal.2019; 60(6): 554.     CrossRef
  • Cohort Profile: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort in Korea
    Jee-Seon Shim, Bo Mi Song, Jung Hyun Lee, Seung Won Lee, Ji Hye Park, Dong Phil Choi, Myung Ha Lee, Kyoung Hwa Ha, Dae Jung Kim, Sungha Park, Won-Woo Lee, Yoosik Youm, Eui-Cheol Shin, Hyeon Chang Kim
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    K.H. Ha, S.A. Kim, Y.M. Lee, D.J. Kim, D.H. Lee
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    Ji Eun Heo, Jee-Seon Shim, Bo Mi Song, Hye Yoon Bae, Ho Jae Lee, Eun Lee, Hyeon Chang Kim
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    Jaewon Yang, Namki Hong, Jee-Seon Shim, Yumie Rhee, Hyeon Chang Kim
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  • Association of appendicular skeletal muscle mass with carotid intima-media thickness according to body mass index in Korean adults
    Ji Eun Heo, Hyeon Chang Kim, Jee-Seon Shim, Bo Mi Song, Hye Yoon Bae, Ho Jae Lee, Il Suh
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  • Comparison of self-reported and accelerometer-assessed measurements of physical activity according to socio-demographic characteristics in Korean adults
    Seung Won Lee, Jee-Seon Shim, Bo Mi Song, Ho Jae Lee, Hye Yoon Bae, Ji Hye Park, Hye Rin Choi, Jae Won Yang, Ji Eun Heo, So Mi Jemma Cho, Ga Bin Lee, Diana Huanan Hidalgo, Tae-Hoon Kim, Kyung Soo Chung, Hyeon Chang Kim
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  • Are Serum Vitamin D Levels Associated With Dry Eye Disease? Results From the Study Group for Environmental Eye Disease
    Da-Hye Jeon, Hyungseon Yeom, Jaewon Yang, Jong Suk Song, Hyung Keun Lee, Hyeon Chang Kim
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Cohort profile
Cancer screenee cohort study of the National Cancer Center in South Korea
Jeongseon Kim
Epidemiol Health. 2014;36:e2014013.   Published online August 6, 2014
DOI: https://doi.org/10.4178/epih/e2014013
  • 17,862 View
  • 204 Download
  • 25 Citations
AbstractAbstract AbstractSummary PDF
Abstract
The Cancer Screenee Cohort Study was first established in 2002 by the National Cancer Center in South Korea to investigate all possible risk factors related to cancers and to expand biological specimen banking for the development of effective methodologies for cancer detection, diagnosis, and prevention. As of July in 2014, total 41,105 participants were enrolled in this cohort. Data were collected via questionnaire, clinical examination, cancer screening, and biological specimen testing including blood, urine, and exfoliated cervical cells. The highest incidence was found to be thyroid cancer, according to a nested case-control study that was linked to the National Cancer Registry information as of December 31, 2011. Case-control, cross-sectional, and cohort studies have been published using these data since 2009. Diet and nutrition was the most published topic, followed by genetics, hepatitis B virus and liver cancer screening, methodologies, physical activity, obesity, metabolic syndrome, smoking and alcohol consumption, and blood type. Evidence from the Cancer Screenee Cohort Study is highly anticipated to reduce the burden of cancer in the Korean population and aid in the detection, diagnosis, and prevention of cancer.
Summary
Korean summary
국립암센터에서는 암을 포함한 만성질환의 포괄적인 위험요인 정보와 생물학적 시료은행을 포함하는 연구기반을 확충하기 위해 2002년 8월부터 지금까지 총 41,104건의 코호트가 구축되고 있다 (2014년 7월 31일 현재). 국립암센터 검진자 코호트 자료를 통해 암발생의 위험요인과 암의 자연사 원인을 규명하고, 역학연구 자원을 활용한 본격적인 암 분자역학 연구를 지원할 수 있을 것으로 기대한다. 뿐만 아니라, 암발생의 유전자-환경 상호작용 규명을 위한 모델을 개발하고, 개인화된 맞춤예방의학(personalized preventive medicine)의 근거지식을 제공할 수 있으며 질병예방 정책 개발 및 적용을 위한 근거를 생산함으로써 우리나라 암관리 정책 사업 평가 및 중장기 연구사업 기획을 위한 자료로 활용될 수 있다.
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Cohort Profile
The Korean social life, health and aging project-health examination cohort
Ju-Mi Lee, Won Joon Lee, Hyeon Chang Kim, Wungrak Choi, Jina Lee, Kiho Sung, Sang Hui Chu, Yeong-Ran Park, Yoosik Youm
Epidemiol Health. 2014;36:e2014003.   Published online May 13, 2014
DOI: https://doi.org/10.4178/epih/e2014003
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AbstractAbstract AbstractSummary PDF
Abstract
The Korean Social Life, Health, and Aging Project (KSHAP) is a population-based longitudinal study of health determinants among elderly Koreans. The target population of the KSHAP are people aged 60 years or older and their spouses living in a rural community of Korea. A complete enumeration survey was conducted in the first wave of the KSHAP on 94.7% (814 of 860) of the target population between December 2011 and July 2012. The KSHAP-Health Examination (KSHAP-HE) cohort consists of 698 people who completed additional health examinations at a public health center (n=533) or at their home (n=165). Face-to-face questionnaires were used to interview participants on their demographics, social network characteristics, medical history, health behaviors, cognitive function, and depression symptoms. Health center examinations included anthropometric measures, body impedance analysis, resting blood pressure measurement, radial artery tonometry, bone densitometry, the timed up-and-go test, and fasting blood analysis. However, only anthropometric measures, blood pressure measurement, and non-fasting blood analysis were available for home health examinations. Collaboration is encouraged and access to the KSHAP baseline data will be available via the website of the Korean Social Science Data Archive (http://www.kossda.or.kr).
Summary
Korean summary
한국인의 사회적 삶, 건강과 노화에 대한 조사(Korean Social Life, Health, and Aging Project, KSHAP) 연구는 노인 건강의 사회적 결정요인과 그 상호작용을 평가하는 것을 목적으로 한다. 이를 위하여 사회연결망분석(social network analysis) 기법을 도입하였다. 사회연결망분석은 개인간의 관계를 네트워크로 파악하는 개념으로, 본 연구에서는 지역사회 전체의 사회연결망 안에서 개인의 특성 및 개인간 상호작용의 특성이 신체적 정신적 건강에 미치는 영향을 연구하고자 한다. 대상인구집단은 인천광역시 강화군 일개 면 지역의 60세 이상 인구 및 그 배우자이며, 전체 860명의 모집단에서 814명(94.7%)의 건강면접조사 및 사회연결망 분석을 완료하였으며, 이 가운데 보건지소(533명) 또는 가정(165명)에서 추가 건강검진을 수행한 698명을 대상으로 KSHAP-Health Examination (KSHAP-HE) 코호트를 구축하였다.
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