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Modifiable risk factors of lung cancer in “never-smoker” women
Jong-Myon Bae
Epidemiol Health. 2015;37:e2015047.   Published online October 29, 2015
DOI: https://doi.org/10.4178/epih/e2015047
  • 15,017 View
  • 208 Download
  • 9 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
Korean women with a history of never smoking and with adenocarcinoma showed an increasing trend in lung cancer occurrence during 2002 to 2012. The two modifiable factors of never-smoker lung cancer in women are hormone and oncogenic virus infection. Based on previous studies, hormone replacement therapy (HRT) and human papillomavirus (HPV) infection might afford protection or be a risk factor, respectively. It is necessary to perform a pooled analysis of cohort studies to evaluate HRT and never-smoker lung cancer in women and a systematic review of case-control studies to determine the association between HPV infection and never-smoker lung cancer.
Summary
Korean summary
2002년에서 2012년간 폐암 통계를 살펴보면 비흡연 여성에서 선암종의 발생이 크게 증가하는 것으로 확인된다. 이렇게 여성에서 비흡연 폐암발생과 관련한 요인들로는 호르몬 대체요법 (HRT)과 인유두종바이러스 (HPV) 감염이 알려져 있다. 환자-대조군연구를 이용한 메타분석에 따르면 호르몬대체요법은 폐암발생을 억제하는 것으로 나왔다. HPV에 대한 메타분석은 아직 없는 가운데 위험요인으로 의심하고 있다. 따라서 HRT에 대하여는 코호트 연구 결과를 이용한 연합분석 (pooled analysis)이 필요하며, HPV에 대하여는 환자-대조군연구 결과를 이용한 메타분석이 수행될 필요가 있다.
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Citations

Citations to this article as recorded by  
  • Endogenous sex hormones, aromatase activity and lung cancer risk in postmenopausal never‐smoking women
    Yingya Zhao, Yu‐Tang Gao, Xianglan Zhang, Alan L. Rockwood, Mark M. Kushnir, Qiuyin Cai, Jie Wu, Jiajun Shi, Qing Lan, Nathaniel Rothman, Yu Shyr, Xiao‐Ou Shu, Wei Zheng, Gong Yang
    International Journal of Cancer.2022; 151(5): 699.     CrossRef
  • Derivation and validation of a prediction model for patients with lung nodules malignancy regardless of mediastinal/hilar lymphadenopathy
    Fenghui Liu, Liping Dai, Yulin Wang, Man Liu, Meng Wang, Zhigang Zhou, Yu Qi, Ruiying Chen, Songyun OuYang, Qingxia Fan
    Journal of Surgical Oncology.2022; 126(8): 1551.     CrossRef
  • The association between circulating docosahexaenoic acid and lung cancer: A Mendelian randomization study
    Hang Zhao, Shengnan Wu, Zhenkai Luo, Hailong Liu, Junwei Sun, Xiaolin Jin
    Clinical Nutrition.2022; 41(11): 2529.     CrossRef
  • Impact of Gut Dysbiosis on the Risk of Non-Small-Cell Lung Cancer
    Yu-Feng Wei, Ming-Shyan Huang, Cheng-Hsieh Huang, Yao-Tsung Yeh, Chih-Hsin Hung
    International Journal of Environmental Research and Public Health.2022; 19(23): 15991.     CrossRef
  • Associations between female lung cancer risk and sex steroid hormones: a systematic review and meta-analysis of the worldwide epidemiological evidence on endogenous and exogenous sex steroid hormones
    Hui Zeng, Zhuoyu Yang, Jiang Li, Yan Wen, Zheng Wu, Yadi Zheng, Yiwen Yu, Yongjie Xu, Shugeng Gao, Fengwei Tan, Ni Li, Qi Xue, Jie He
    BMC Cancer.2021;[Epub]     CrossRef
  • Lung Cancer in Never-Smokers: A Multicenter Case-Control Study in North China
    Di Liang, Jingxi Wang, Daojuan Li, Jin Shi, Jin Jing, Baoen Shan, Yutong He
    Frontiers in Oncology.2019;[Epub]     CrossRef
  • Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
    Jong-Myon Bae
    Journal of Preventive Medicine and Public Health.2018; 51(5): 263.     CrossRef
  • Age at menopause and hormone replacement therapy as risk factors for head and neck and oesophageal cancer
    Caroline E. McCarthy, John K. Field, Michael W. Marcus
    Oncology Reports.2017; 38(4): 1915.     CrossRef
  • Human papillomavirus infection and risk of lung cancer in never-smokers and women: an ‘adaptive’ meta-analysis
    Jong-Myon Bae, Eun Hee Kim
    Epidemiology and Health.2015; 37: e2015052.     CrossRef
The necessity of an observational study on the interactions between allergic history and citrus fruit intake for the prevention of pancreatic cancer
Jong-Myon Bae
Epidemiol Health. 2015;37:e2015028.   Published online June 16, 2015
DOI: https://doi.org/10.4178/epih/e2015028
  • 15,235 View
  • 160 Download
  • 4 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
While the main product of Jeju Island is citrus fruit and the prevalence of atopic dermatitis among the students who live there is relatively high, the incidence of pancreatic cancer is lowest in Korea. Systematic reviews reporting allergic history and intake of citrus fruit as protective factors against pancreatic cancer (PCC) were published in 2005 and 2008, respectively. Although there were discrepancies in the results of the subgroup analyses between case-control and cohort studies, it is necessary to evaluate an interaction effect between allergic history and intake of citrus fruits on PCC risk.
Summary
Korean summary
췌장암 발생과 관련한 요인들의 규명이 절실한 상황에서, 알레르기 질환과 감귤섭취 각각이 발생억제 효과가 있다는 체계적 고찰연구가 있다. 그러나 코호트 연구들만으로 메타분석을 하였을 때는 두 억제 요인 모두 통계적 유의성이 없는 것으로 나왔다. 한편 지역별 췌장암 발생률에서 낮은 수준을 보이는 제주도는 주요 감귤생산지이면서, 초중고등학생의 아토피 유병률이 상대적으로 높은 것으로 알려져 있다. 이런 사실들에 근거할 때 췌장암 발생에 있어 알레르기질환과 감귤섭취의 상호작용을 규명하는 코호트 연구를 제안한다.
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Citations

Citations to this article as recorded by  
  • Citation Discovery Tools for Conducting Adaptive Meta-analyses to Update Systematic Reviews
    Jong-Myon Bae, Eun Hee Kim
    Journal of Preventive Medicine and Public Health.2016; 49(2): 129.     CrossRef
  • Hormonal Replacement Therapy and the Risk of Lung Cancer in Women: An Adaptive Meta-analysis of Cohort Studies
    Jong-Myon Bae, Eun Hee Kim
    Journal of Preventive Medicine and Public Health.2015; 48(6): 280.     CrossRef
  • Human papillomavirus infection and risk of lung cancer in never-smokers and women: an ‘adaptive’ meta-analysis
    Jong-Myon Bae, Eun Hee Kim
    Epidemiology and Health.2015; 37: e2015052.     CrossRef
  • Hormone Replacement Therapy and Risk of Breast Cancer in Korean Women: A Quantitative Systematic Review
    Jong-Myon Bae, Eun Hee Kim
    Journal of Preventive Medicine and Public Health.2015; 48(5): 225.     CrossRef
Two hypotheses of dense breasts and viral infection for explaining incidence of breast cancer by age group in Korean women
Jong-Myon Bae
Epidemiol Health. 2014;36:e2014020.   Published online September 26, 2014
DOI: https://doi.org/10.4178/epih/e2014020
  • 17,138 View
  • 135 Download
  • 13 Citations
AbstractAbstract PDFSupplementary Material
Abstract
Breast cancer, the second leading type of cancer in Korean women, has shown increasing incidence over the past 10 years. However, the curves of incidence by age group cast doubt on the birth cohort effect hypothesis. To explain the curves, here I suggest two alternative hypotheses of breast density and viral infection based on pre-existing evidences. Evaluating these hypotheses would require important clues to find unknown risk factors of breast cancer and to plan more effective strategies for breast cancer control in Korean women.
Summary
Korean summary
Key Message

Citations

Citations to this article as recorded by  
  • A Historical Misconception in Clinical Trials of Drugs for Cancer—Age Grouping
    Jingyu Chen, Lan Yao, Abdulmohsin J. Alamoudi, Lotfi Aleya, Weikuan Gu
    Journal of Personalized Medicine.2022; 12(12): 1998.     CrossRef
  • Association between changes in mammographic density category and the risk of breast cancer: A nationwide cohort study in East‐Asian women
    Soyeoun Kim, Boyoung Park
    International Journal of Cancer.2021; 148(11): 2674.     CrossRef
  • History of Diabetes Mellitus and Risk of Breast Cancer in Asian Women: A Meta-Epidemiological Analysis of Population-Based Cohort Studies
    Jong-Myon Bae
    Journal of Menopausal Medicine.2020; 26(1): 29.     CrossRef
  • Human papilloma virus and breast cancer: the role of inflammation and viral expressed proteins
    Niloofar Khodabandehlou, Shayan Mostafaei, Ashkan Etemadi, Amir Ghasemi, Mehrdad Payandeh, Shima Hadifar, Amir Hossein Norooznezhad, Anoshirvan Kazemnejad, Mohsen Moghoofei
    BMC Cancer.2019;[Epub]     CrossRef
  • Researches of Epigenetic Epidemiology for Infections and Radiation as Carcinogen
    Jong-Myon Bae
    Journal of Preventive Medicine and Public Health.2018; 51(4): 169.     CrossRef
  • Factors Influencing Background Parenchymal Enhancement on Breast MRI Classified by Mammographic Density
    Natsuko Kunimatsu, Akira Kunimatsu, Yoshihiro Uchida, Sachiko Inano, Shigeru Nawano
    The KITAKANTO Medical Journal.2017; 67(3): 213.     CrossRef
  • Epstein-Barr Virus Infection and Risk of Breast Cancer: An Adaptive Meta-Analysis for Case-Control Studies
    Jong-Myon Bae, Eun Hee Kim
    Archives of Clinical Infectious Diseases.2016;[Epub]     CrossRef
  • Breast Density and Risk of Breast Cancer in Asian Women: A Meta-analysis of Observational Studies
    Jong-Myon Bae, Eun Hee Kim
    Journal of Preventive Medicine and Public Health.2016; 49(6): 367.     CrossRef
  • Hormone Replacement Therapy and Risk of Breast Cancer in Korean Women: A Quantitative Systematic Review
    Jong-Myon Bae, Eun Hee Kim
    Journal of Preventive Medicine and Public Health.2015; 48(5): 225.     CrossRef
  • Modifiable risk factors of lung cancer in “never-smoker” women
    Jong-Myon Bae
    Epidemiology and Health.2015; 37: e2015047.     CrossRef
  • Human papillomavirus 16 infection as a potential risk factor for prostate cancer: an adaptive meta-analysis
    Jong-Myon Bae
    Epidemiology and Health.2015; 37: e2015005.     CrossRef
  • Human papillomavirus infection and risk of lung cancer in never-smokers and women: an ‘adaptive’ meta-analysis
    Jong-Myon Bae, Eun Hee Kim
    Epidemiology and Health.2015; 37: e2015052.     CrossRef
  • Distribution of Dense Breasts using Screening Mammography in Korean Women: a Retrospecitive Observational Study
    Jong-Myon Bae, Sang Yop Shin, Eun Hee Kim, Yoon-Nma Kim, Chung Mo Nam
    Epidemiology and Health.2014; : e2014027.     CrossRef

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